Moving towards tissue-engineered disc replacement
نویسندگان
چکیده
منابع مشابه
Tissue-engineered total disc replacement: final outcomes of a murine caudal disc in vivo study
Consistent with EBSJ's commitment to fostering quality research, we are pleased to feature some of the most highly rated abstracts from the 9th Annual AOSpine North America Fellows Forum in Banff, Canada. Enhancing the quality of evidence in spine care means acknowledging and supporting the efforts of young researchers within our AOSpine North America network. We look forward to seeing more fro...
متن کاملTissue Engineered Disc Replacement. Long term outcome in a rat spinal model
INTRODUCTION Degeneration of the intervertebral discs (IVD) in the human spine is a common and frequent occurrence. It is associated with symptomatic presentations in patients with cervical of lumbar complaints. In the US in excess of 200,000 surgeries per year are performed to either replace the IVD, currently with a mechanical construct, or to fuse the adjacent vertebral bones. Mechanical rep...
متن کاملTotal disc replacement using tissue-engineered intervertebral discs in the canine cervical spine
The most common reason that adults in the United States see their physician is lower back or neck pain secondary to degenerative disc disease. To date, approaches to treat degenerative disc disease are confined to purely mechanical devices designed to either eliminate or enable flexibility of the diseased motion segment. Tissue engineered intervertebral discs (TE-IVDs) have been proposed as an ...
متن کاملTotal disc replacement using a tissue-engineered intervertebral disc in vivo: new animal model and initial results
STUDY TYPE Basic science Introduction: Chronic back pain due to degenerative disc disease (DDD) is among the most important medical conditions causing morbidity and significant health care costs. Surgical treatment options include disc replacement or fusion surgery, but are associated with significant short- and long-term risks.1 Biological tissue-engineering of human intervertebral discs (IV...
متن کاملStem Cell‐Based Tissue‐Engineered Laryngeal Replacement
: Patients with laryngeal disorders may have severe morbidity relating to swallowing, vocalization, and respiratory function, for which conventional therapies are suboptimal. A tissue-engineered approach would aim to restore the vocal folds and maintain respiratory function while limiting the extent of scarring in the regenerated tissue. Under Good Laboratory Practice conditions, we decellulari...
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2019
ISSN: 1759-4790,1759-4804
DOI: 10.1038/s41584-019-0159-0